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Your Vote Counts! TACTILE SYSTEMS TECHNOLOGY, INC. 2021 Annual Meeting Vote by May 16, 2021 11:59 PM ET TACTILE SYSTEMS TECHNOLOGY, INC. 3701 WAYZATA BLVD. SUITE 300 MINNEAPOLIS, MN 55416 D35855-P49962 You invested in TACTILE SYSTEMS TECHNOLOGY, INC. and it’s time to vote! This is an Important Notice Regarding the Availability of Proxy Materials for the Stockholder Meeting to be Held on May 17, 2021. Get informed before you vote View the Notice and Proxy Statement and Annual Report online OR you can receive a free paper copy of voting material(s) by requesting prior to May 3, 2021. If you would like to request a copy of the voting material(s), you may (1) visit www.ProxyVote.com, (2) call 1-800-579-1639 or (3) send an email to [email protected]. If sending an email, please include your control number (indicated below) in the subject line. Smartphone users Point your camera here and view materials and vote without entering a control number Vote Virtually at the Meeting* May 17, 2021 9:00 AM, CDT Virtually at: www.virtualshareholdermeeting.com/TCMD2021 *Many stockholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance. V1 For complete information and to vote, visit www.ProxyVote.com Control #

Vote at www.ProxyVote.com THIS IS NOT A VOTABLE BALLOT This is an overview of the more complete proxy materials that are available on the Internet or by mail. You may view the proxy materials online at www.proxyvote.com or easily request a paper copy (see reverse side). We encourage you to access and review all of the important information contained in the proxy materials before voting. Board Recommends Voting Items D35856-P49962 Prefer to receive an email instead? While voting on www.ProxyVote.com, be sure to click “Sign up for E-delivery”. 1. Elect eight directors Nominees: 01) William Burke05) Richard Nigon 02) Sheri Dodd06) Daniel Reuvers 03) Raymond Huggenberger07) Kevin Roche 04) Deepti Jain08) Peter Soderberg For 2. Ratify the appointment of Grant Thornton LLP as our independent registered public accounting firm for the year ending December 31, 2021. For 3. Approve, on an advisory basis, the 2020 compensation of our named executive officers. For NOTE: In their discretion, the proxies are authorized to vote on such other business as may properly come before the meeting or any adjournment thereof.